5X1O
PI(4,5)P2 lipid binding induced a reorientation of FGF2 molecules near membrane surface to facilitate the unconventional oligomerization-dependent secretion process as revealed by a combined FTIR/NMR/X-ray study
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Fibroblast growth factor 2 | polymer | 146 | 16435.9 | 2 | UniProt (P09038) Pfam (PF00167) | Homo sapiens (Human) | FGF-2,Basic fibroblast growth factor,bFGF,Heparin-binding growth factor 2,HBGF-2 |
| 2 | C, D (A) | D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE | non-polymer | 420.1 | 2 | Chemie (I3P) | |||
| 3 | E, F (A, B) | water | water | 18.0 | 197 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 32871.7 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 840.2 | |
| All* | Total formula weight | 33711.9 |
