5X0T

Crystal structure of CD147 C2 domain in complex with Fab of its monoclonal antibody 6H8

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, C)	6H8 Fab fragment heavy chain	polymer	241	26331.7	2		Mus musculus (Mouse)
2	C, D (B, D)	6H8 Fab fragment light chain	polymer	234	25913.7	2		Mus musculus (Mouse)
3	E, F (E, F)	Basigin	polymer	89	9840.0	2	UniProt (P35613)	Homo sapiens (Human)	CD147
4	G, H, I, J, K... (A, C, B, D, E...)	water	water		18.0	189	Chemie (HOH)

Sequence modifications

E, F: 22 - 101 (UniProt: P35613)

PDB	External Database	Details
Met 21	-	expression tag
Leu 102	-	expression tag
Glu 103	-	expression tag
His 104	-	expression tag
His 105	-	expression tag
His 106	-	expression tag
His 107	-	expression tag
His 108	-	expression tag
His 109	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	124170.7
All*	Total formula weight	124170.7

*Water molecules are not included.