5X0T

Crystal structure of CD147 C2 domain in complex with Fab of its monoclonal antibody 6H8

Functional Information from GO Data

Chain	GOid	namespace	contents
E	0005886	cellular_component	plasma membrane
E	0007155	biological_process	cell adhesion
E	0007411	biological_process	axon guidance
F	0005886	cellular_component	plasma membrane
F	0007155	biological_process	cell adhesion
F	0007411	biological_process	axon guidance

Functional Information from PROSITE/UniProt

site_id	PS00290
Number of Residues	7
Details	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YTCEATH

Chain	Residue	Details
B	TYR212-HIS218

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"12754519","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19159218","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19349973","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	8
Details	Region: {"description":"Essential for interaction with KDR/VEGFR2","evidences":[{"source":"PubMed","id":"25825981","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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