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5WZY

Crystal structure of the P2X4 receptor from zebrafish in the presence of CTP at 2.8 Angstroms

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
p2X purinoceptorpolymer34038117.61UniProt (Q6NYR1)
Pfam (PF00864)
UniProt (by SIFTS) (F8W463)
Danio rerio (Zebrafish)
2B
(B)
alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranosebranched1073.01In PDB
GlyTouCan (G42984ZU)
3C
(A)
2-acetamido-2-deoxy-beta-D-glucopyranosenon-polymer221.21Chemie (NAG)
4D, E
(A)
GLYCEROLnon-polymer92.12Chemie (GOL)
5F
(A)
CYTIDINE-5'-TRIPHOSPHATEnon-polymer483.21Chemie (CTP)
6G
(A)
waterwater18.072Chemie (HOH)
Sequence modifications
A: 28 - 365 (UniProt: Q6NYR1)
PDBExternal DatabaseDetails
Gly 26-expression tag
Ser 27-expression tag
Lys 78Asn 78conflict
Arg 187Asn 187conflict
Arg 252His 252conflict
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight38117.6
BranchedNumber of molecules1
Total formula weight1073.0
Non-Polymers*Number of molecules4
Total formula weight888.6
All*Total formula weight40079.1
*Water molecules are not included.

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PDB entries from 2025-06-11

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