5WZY
Crystal structure of the P2X4 receptor from zebrafish in the presence of CTP at 2.8 Angstroms
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | p2X purinoceptor | polymer | 340 | 38117.6 | 1 | UniProt (Q6NYR1) Pfam (PF00864) UniProt (by SIFTS) (F8W463) In PDB | Danio rerio (Zebrafish) | |
| 2 | B | alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1073.0 | 1 | In PDB GlyTouCan (G42984ZU) | |||
| 3 | A | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
| 4 | A | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 5 | A | CYTIDINE-5'-TRIPHOSPHATE | non-polymer | 483.2 | 1 | Chemie (CTP) | |||
| 6 | water | water | 18.0 | 72 | Chemie (HOH) |
Sequence modifications
A: 28 - 365 (UniProt: Q6NYR1)
| PDB | External Database | Details |
|---|---|---|
| Gly 26 | - | expression tag |
| Ser 27 | - | expression tag |
| Lys 78 | Asn 78 | conflict |
| Arg 187 | Asn 187 | conflict |
| Arg 252 | His 252 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 38117.6 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 1073.0 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 888.6 | |
| All* | Total formula weight | 40079.1 |
