5WZX
Structural basis for a pentacyclic oleanane-type triterpenoid as a ligand of FXR
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Bile acid receptor | polymer | 228 | 26674.7 | 2 | UniProt (Q96RI1) Pfam (PF00104) In PDB | Homo sapiens (Human) | Farnesoid X-activated receptor,Farnesol receptor HRR-1,Nuclear receptor subfamily 1 group H member 4,Retinoid X receptor-interacting protein 14,RXR-interacting protein 14 |
| 2 | C, D | SRC2-3 peptide from Nuclear receptor coactivator 2 | polymer | 12 | 1464.7 | 2 | UniProt (Q15596) In PDB | Homo sapiens | |
| 3 | A, B | (4aR,6aR,6aS,6bS,8aS,9R,12aR,14bR)-2,2,6a,6b,9,12a-hexamethyl-10-oxidanylidene-1,3,4,5,6,6a,7,8,8a,9,11,12,13,14b-tetradecahydropicene-4a-carboxylic acid | non-polymer | 440.7 | 2 | Chemie (7VX) | |||
| 4 | A | (R,R)-2,3-BUTANEDIOL | non-polymer | 90.1 | 3 | Chemie (BU3) | |||
| 5 | water | water | 18.0 | 38 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 56278.6 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 1151.7 | |
| All* | Total formula weight | 57430.3 |
