5WXT
Crystal structure of uPA-S195A in complex with S2444
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (U) | Urokinase-type plasminogen activator chain B | polymer | 253 | 28426.4 | 1 | UniProt (P00749) Pfam (PF00089) | Homo sapiens (Human) | uPA |
| 2 | B (U) | 5-oxo-D-prolylglycyl-N-(4-nitrophenyl)-L-argininamide | non-polymer | 462.5 | 1 | BIRD (PRD_002229) Chemie (7YR) | |||
| 3 | C (U) | water | water | 18.0 | 52 | Chemie (HOH) |
Sequence modifications
U: 16 - 250 (UniProt: P00749)
| PDB | External Database | Details |
|---|---|---|
| Ala 122 | Cys 299 | engineered mutation |
| Gln 145 | Asn 322 | engineered mutation |
| Ala 195 | Ser 376 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 28426.4 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 462.5 | |
| All* | Total formula weight | 28888.8 |
