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5WSB

Pyruvate kinase (PYK) from Mycobacterium tuberculosis in complex with Oxalate, allosteric activators AMP and Glucose 6-Phosphate

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, DPyruvate kinasepolymer47551014.34UniProt (P9WKE5)
Pfam (PF00224)
Pfam (PF02887)
In PDB
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)PK
2A, B, C, DADENOSINE MONOPHOSPHATEnon-polymer347.24Chemie (AMP)
3A, B, C, D6-O-phosphono-alpha-D-glucopyranosenon-polymer260.14Chemie (G6P)
4A, B, C, DMAGNESIUM IONnon-polymer24.34Chemie (MG)
5A, B, C, DOXALATE IONnon-polymer88.04Chemie (OXL)
6BPOTASSIUM IONnon-polymer39.11Chemie (K)
7C, DPHOSPHATE IONnon-polymer95.02Chemie (PO4)
8waterwater18.0410Chemie (HOH)
Sequence modifications
A, B, C, D: 1 - 472 (UniProt: P9WKE5)
PDBExternal DatabaseDetails
Gly -2-expression tag
Gly -1-expression tag
His 0-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight204057.3
Non-Polymers*Number of molecules19
Total formula weight3107.8
All*Total formula weight207165.1
*Water molecules are not included.

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PDB entries from 2024-07-10

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