5WSB
Pyruvate kinase (PYK) from Mycobacterium tuberculosis in complex with Oxalate, allosteric activators AMP and Glucose 6-Phosphate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Pyruvate kinase | polymer | 475 | 51014.3 | 4 | UniProt (P9WKE5) Pfam (PF00224) Pfam (PF02887) | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) | PK |
| 2 | E, I, N, S (A, B, C, D) | ADENOSINE MONOPHOSPHATE | non-polymer | 347.2 | 4 | Chemie (AMP) | |||
| 3 | F, J, O, T (A, B, C, D) | 6-O-phosphono-alpha-D-glucopyranose | non-polymer | 260.1 | 4 | Chemie (G6P) | |||
| 4 | G, K, P, U (A, B, C, D) | MAGNESIUM ION | non-polymer | 24.3 | 4 | Chemie (MG) | |||
| 5 | H, L, Q, V (A, B, C, D) | OXALATE ION | non-polymer | 88.0 | 4 | Chemie (OXL) | |||
| 6 | M (B) | POTASSIUM ION | non-polymer | 39.1 | 1 | Chemie (K) | |||
| 7 | R, W (C, D) | PHOSPHATE ION | non-polymer | 95.0 | 2 | Chemie (PO4) | |||
| 8 | AA, X, Y, Z (D, A, B, C) | water | water | 18.0 | 410 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 472 (UniProt: P9WKE5)
| PDB | External Database | Details |
|---|---|---|
| Gly -2 | - | expression tag |
| Gly -1 | - | expression tag |
| His 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 204057.3 | |
| Non-Polymers* | Number of molecules | 19 |
| Total formula weight | 3107.8 | |
| All* | Total formula weight | 207165.1 |
