5WSB

Pyruvate kinase (PYK) from Mycobacterium tuberculosis in complex with Oxalate, allosteric activators AMP and Glucose 6-Phosphate

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000287	molecular_function	magnesium ion binding
A	0004743	molecular_function	pyruvate kinase activity
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0005886	cellular_component	plasma membrane
A	0006096	biological_process	glycolytic process
A	0030955	molecular_function	potassium ion binding
B	0000287	molecular_function	magnesium ion binding
B	0004743	molecular_function	pyruvate kinase activity
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0005886	cellular_component	plasma membrane
B	0006096	biological_process	glycolytic process
B	0030955	molecular_function	potassium ion binding
C	0000287	molecular_function	magnesium ion binding
C	0004743	molecular_function	pyruvate kinase activity
C	0005737	cellular_component	cytoplasm
C	0005829	cellular_component	cytosol
C	0005886	cellular_component	plasma membrane
C	0006096	biological_process	glycolytic process
C	0030955	molecular_function	potassium ion binding
D	0000287	molecular_function	magnesium ion binding
D	0004743	molecular_function	pyruvate kinase activity
D	0005737	cellular_component	cytoplasm
D	0005829	cellular_component	cytosol
D	0005886	cellular_component	plasma membrane
D	0006096	biological_process	glycolytic process
D	0030955	molecular_function	potassium ion binding

Functional Information from PROSITE/UniProt

site_id	PS00110
Number of Residues	13
Details	PYRUVATE_KINASE Pyruvate kinase active site signature. VpVIAKLEKpEAI

Chain	Residue	Details
A	VAL213-ILE225

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	32
Details	Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	20
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"P14618","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	4
Details	Site: {"description":"Transition state stabilizer","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI4
Number of Residues	4
Details	Modified residue: {"description":"Phosphoserine; by PknJ; in vitro","evidences":[{"source":"PubMed","id":"20520732","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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