5WRJ
Crystal structure of human tyrosylprotein sulfotransferase-1 complexed with PAP and gastrin peptide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Protein-tyrosine sulfotransferase 1 | polymer | 303 | 34373.3 | 4 | UniProt (O60507) Pfam (PF13469) | Homo sapiens (Human) | Tyrosylprotein sulfotransferase 1,TPST-1 |
| 2 | E, F, G, H (F, H, J, L) | gastrin peptide | polymer | 12 | 1534.6 | 4 | Pfam (PF00918) UniProt (by SIFTS) (P01350) | synthetic construct | |
| 3 | I, K, M, O (A, B, C, D) | ADENOSINE-3'-5'-DIPHOSPHATE | non-polymer | 427.2 | 4 | Chemie (A3P) | |||
| 4 | J, L, N, P (A, B, C, D) | MAGNESIUM ION | non-polymer | 24.3 | 4 | Chemie (MG) | |||
| 5 | Q, R, S, T (A, B, C, D) | water | water | 18.0 | 144 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 43 - 341 (UniProt: O60507)
| PDB | External Database | Details |
|---|---|---|
| Gly 39 | - | expression tag |
| Ser 40 | - | expression tag |
| His 41 | - | expression tag |
| Met 42 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 143631.3 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 1806.0 | |
| All* | Total formula weight | 145437.3 |
