5WRI
Crystal structure of human tyrosylprotein sulfotransferase-1 complexed with PAP and C4 peptide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Protein-tyrosine sulfotransferase 1 | polymer | 320 | 36262.3 | 2 | UniProt (O60507) Pfam (PF13469) | Homo sapiens (Human) | Tyrosylprotein sulfotransferase 1,TPST-1 |
| 2 | C, D (D, E) | ASP-PHE-GLU-ASP-TYR-GLU-PHE-ASP | polymer | 8 | 1079.0 | 2 | synthetic construct | ||
| 3 | E, H (A, B) | ADENOSINE-3'-5'-DIPHOSPHATE | non-polymer | 427.2 | 2 | Chemie (A3P) | |||
| 4 | F, I (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 5 | G (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 6 | J (B) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 7 | K, L, M, N (A, B, D, E) | water | water | 18.0 | 571 | Chemie (HOH) |
Sequence modifications
A, B: 43 - 341 (UniProt: O60507)
| PDB | External Database | Details |
|---|---|---|
| Met 22 | - | expression tag |
| Gly 23 | - | expression tag |
| Ser 24 | - | expression tag |
| Ser 25 | - | expression tag |
| His 26 | - | expression tag |
| His 27 | - | expression tag |
| His 28 | - | expression tag |
| His 29 | - | expression tag |
| His 30 | - | expression tag |
| His 31 | - | expression tag |
| Ser 32 | - | expression tag |
| Ser 33 | - | expression tag |
| Gly 34 | - | expression tag |
| Leu 35 | - | expression tag |
| Val 36 | - | expression tag |
| Pro 37 | - | expression tag |
| Arg 38 | - | expression tag |
| Gly 39 | - | expression tag |
| Ser 40 | - | expression tag |
| His 41 | - | expression tag |
| Met 42 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 74682.8 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 1060.5 | |
| All* | Total formula weight | 75743.3 |
