5WPT
Cryo-EM structure of mammalian endolysosomal TRPML1 channel in nanodiscs in closed II conformation at 3.75 Angstrom resolution
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D | Mucolipin-1 | polymer | 592 | 66656.8 | 4 | UniProt (Q99J21) Pfam (PF21381) Pfam (PF00520) Pfam (PF08016) In PDB | Mus musculus (Mouse) | TRPML1, Mucolipidin |
| 2 | E, F, G, H | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 4 | In PDB GlyTouCan (G42666HT) | |||
| 3 | A | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) |
Sequence modifications
A, B, C, D: 1 - 580 (UniProt: Q99J21)
| PDB | External Database | Details |
|---|---|---|
| Val 581 | - | expression tag |
| Asp 582 | - | expression tag |
| Gly 583 | - | expression tag |
| Gly 584 | - | expression tag |
| Ser 585 | - | expression tag |
| Ser 586 | - | expression tag |
| Gly 587 | - | expression tag |
| Gly 588 | - | expression tag |
| Leu 589 | - | expression tag |
| Val 590 | - | expression tag |
| Pro 591 | - | expression tag |
| Arg 592 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 266627.2 | |
| Branched | Number of molecules | 4 |
| Total formula weight | 1697.6 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 23.0 | |
| All* | Total formula weight | 268347.8 |
