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5WO8

Crystal Structure of Transient Receptor Potential (TRP) channel TRPV6*-Del1

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Transient receptor potential cation channel subfamily V member 6polymer67277133.51UniProt (Q9R186)
Pfam (PF12796)
Pfam (PF00520)
Rattus norvegicus (Rat)TrpV6,Calcium transport protein 1,CaT1,Epithelial calcium channel 2,ECaC2
2B
(A)
6-(5-METHYL-2-OXO-IMIDAZOLIDIN-4-YL)-HEXANOIC ACIDnon-polymer214.31Chemie (DTB)
3C
(A)
CALCIUM IONnon-polymer40.11Chemie (CA)
Sequence modifications
A: 1 - 669 (UniProt: Q9R186)
PDBExternal DatabaseDetails
Tyr 62Ile 102engineered mutation
Asn 92Leu 132engineered mutation
Gln 96Met 136engineered mutation
Val 670-expression tag
Pro 671-expression tag
Arg 672-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight77133.5
Non-Polymers*Number of molecules2
Total formula weight254.3
All*Total formula weight77387.8
*Water molecules are not included.

246031

PDB entries from 2025-12-10

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