5WNJ
Crystal structure of murine receptor-interacting protein kinase 4 (Ripk4) D143N in complex with lestaurtinib
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Receptor-interacting serine/threonine-protein kinase 4 | polymer | 342 | 38988.0 | 1 | UniProt (Q9ERK0) Pfam (PF00069) | Mus musculus (Mouse) | Ankyrin repeat domain-containing protein 3,PKC-associated protein kinase,PKC-regulated protein kinase |
| 2 | B (A) | Lestaurtinib | non-polymer | 439.5 | 1 | Chemie (2V9) | |||
| 3 | C (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 4 | D (A) | water | water | 18.0 | 24 | Chemie (HOH) |
Sequence modifications
A: 1 - 342 (UniProt: Q9ERK0)
| PDB | External Database | Details |
|---|---|---|
| Asn 143 | Asp 143 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 38988.0 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 474.9 | |
| All* | Total formula weight | 39463.0 |
