5WLY
E. coli LpxH- 8 mutations
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A (A) | UDP-2,3-diacylglucosamine hydrolase | polymer | 248 | 27732.0 | 1 | UniProt (Q0P6L0) Pfam (PF00149) UniProt (by SIFTS) (P43341) | Escherichia coli | UDP-2,3-diacylglucosamine diphosphatase |
2 | B, C (A) | MANGANESE (II) ION | non-polymer | 54.9 | 2 | Chemie (MN) | |||
3 | D (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
4 | E (A) | FORMIC ACID | non-polymer | 46.0 | 1 | Chemie (FMT) | |||
5 | F (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
6 | G (A) | water | water | 18.0 | 149 | Chemie (HOH) |
Sequence modifications
A: 1 - 240 (UniProt: Q0P6L0)
PDB | External Database | Details |
---|---|---|
Ala 14 | Glu 14 | engineered mutation |
Ala 15 | Glu 15 | engineered mutation |
His 141 | Phe 141 | engineered mutation |
Ser 142 | Leu 142 | engineered mutation |
Ser 146 | Leu 146 | engineered mutation |
His 147 | Phe 147 | engineered mutation |
Thr 161 | Lys 161 | engineered mutation |
Ala 162 | Glu 162 | engineered mutation |
Leu 241 | - | expression tag |
Glu 242 | - | expression tag |
His 243 | - | expression tag |
His 244 | - | expression tag |
His 245 | - | expression tag |
His 246 | - | expression tag |
His 247 | - | expression tag |
His 248 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 27732.0 | |
Non-Polymers* | Number of molecules | 5 |
Total formula weight | 253.4 | |
All* | Total formula weight | 27985.4 |