5WLY
E. coli LpxH- 8 mutations
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0006629 | biological_process | lipid metabolic process |
| A | 0008758 | molecular_function | UDP-2,3-diacylglucosamine hydrolase activity |
| A | 0009245 | biological_process | lipid A biosynthetic process |
| A | 0016462 | molecular_function | pyrophosphatase activity |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0019897 | cellular_component | extrinsic component of plasma membrane |
| A | 0030145 | molecular_function | manganese ion binding |
| A | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | binding site for residue MN A 301 |
| Chain | Residue |
| A | ASP41 |
| A | ASN79 |
| A | HIS114 |
| A | HIS195 |
| A | MN302 |
| A | HOH411 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | binding site for residue MN A 302 |
| Chain | Residue |
| A | HIS197 |
| A | MN301 |
| A | HOH411 |
| A | ASP8 |
| A | HIS10 |
| A | ASP41 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue CL A 303 |
| Chain | Residue |
| A | ASN79 |
| A | ARG80 |
| A | ARG155 |
| A | HOH429 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | binding site for residue EDO A 305 |
| Chain | Residue |
| A | ASN53 |
| A | HOH401 |
| A | HOH427 |
