5WI8

Crystal structure of murine 4-1BB from HEK293T cells in P21 space group

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Tumor necrosis factor receptor superfamily member 9	polymer	143	15643.9	4	UniProt (P20334) Pfam (PF00020)	Mus musculus (Mouse)	4-1BB ligand receptor,T-cell antigen 4-1BB
2	E (E)	beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose	branched		732.7	1	In PDB GlyTouCan (G32152BH)
3	F, H (F, H)	alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose	branched		894.8	2	In PDB GlyTouCan (G00395TQ)
4	G (G)	alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		748.7	1	In PDB GlyTouCan (G81315DD)
5	I, J, K, L, M... (A, B, C, D)	GLYCEROL	non-polymer		92.1	9	Chemie (GOL)
6	N, P, Q, R, U... (A, B, C, D)	1,2-ETHANEDIOL	non-polymer		62.1	8	Chemie (EDO)
7	S (B)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	1	Chemie (NAG)
8	AA, BA, CA, DA (A, B, C, D)	water	water		18.0	91	Chemie (HOH)

Sequence modifications

A, B, C, D: 24 - 160 (UniProt: P20334)

PDB	External Database	Details
Leu 22	-	expression tag
Glu 23	-	expression tag
Leu 161	-	expression tag
Val 162	-	expression tag
Pro 163	-	expression tag
Arg 164	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	62575.4
Branched	Number of molecules	4
	Total formula weight	3271.0
Non-Polymers*	Number of molecules	18
	Total formula weight	1546.6
All*	Total formula weight	67393.0

*Water molecules are not included.