5WI8
Crystal structure of murine 4-1BB from HEK293T cells in P21 space group
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0006915 | biological_process | apoptotic process |
| A | 0008285 | biological_process | negative regulation of cell population proliferation |
| A | 0009897 | cellular_component | external side of plasma membrane |
| A | 0038023 | molecular_function | signaling receptor activity |
| B | 0006915 | biological_process | apoptotic process |
| B | 0008285 | biological_process | negative regulation of cell population proliferation |
| B | 0009897 | cellular_component | external side of plasma membrane |
| B | 0038023 | molecular_function | signaling receptor activity |
| C | 0006915 | biological_process | apoptotic process |
| C | 0008285 | biological_process | negative regulation of cell population proliferation |
| C | 0009897 | cellular_component | external side of plasma membrane |
| C | 0038023 | molecular_function | signaling receptor activity |
| D | 0006915 | biological_process | apoptotic process |
| D | 0008285 | biological_process | negative regulation of cell population proliferation |
| D | 0009897 | cellular_component | external side of plasma membrane |
| D | 0038023 | molecular_function | signaling receptor activity |
Functional Information from PROSITE/UniProt
| site_id | PS00652 |
| Number of Residues | 41 |
| Details | TNFR_NGFR_1 TNFR/NGFR family cysteine-rich region signature. Cppst..Fssiggqpn..CniCrv.Cagyfrfkkf..CssthnaECEC |
| Chain | Residue | Details |
| A | CYS47-CYS87 |
| site_id | PS01186 |
| Number of Residues | 14 |
| Details | EGF_2 EGF-like domain signature 2. CeCieGFhclgpq..C |
| Chain | Residue | Details |
| A | CYS85-CYS98 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 156 |
| Details | Repeat: {"description":"TNFR-Cys 2"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 124 |
| Details | Repeat: {"description":"TNFR-Cys 3"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 164 |
| Details | Repeat: {"description":"TNFR-Cys 4"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 8 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
