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5WI1

Crystal structure of human NAMPT with fragment 5: (3E)-3-[(phenylamino)methylidene]oxan-2-one

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Nicotinamide phosphoribosyltransferasepolymer49155594.92UniProt (P43490)
Pfam (PF18127)
Pfam (PF04095)
Homo sapiens (Human)Nampt,Pre-B-cell colony-enhancing factor 1,Pre-B cell-enhancing factor,Visfatin
2C, E
(A, B)
(3E)-3-[(phenylamino)methylidene]oxan-2-onenon-polymer203.22Chemie (AOY)
3D, F
(A, B)
SULFATE IONnon-polymer96.12Chemie (SO4)
4G, H
(A, B)
waterwater18.0538Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight111189.9
Non-Polymers*Number of molecules4
Total formula weight598.6
All*Total formula weight111788.5
*Water molecules are not included.

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PDB entries from 2025-08-06

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