5WI0
Crystal structure of human NAMPT with fragment 2: 2-[(2-fluorophenyl)amino]-6-propylpyrimidin-4(3H)-one
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Nicotinamide phosphoribosyltransferase | polymer | 491 | 55594.9 | 2 | UniProt (P43490) Pfam (PF18127) Pfam (PF04095) | Homo sapiens (Human) | Nampt,Pre-B-cell colony-enhancing factor 1,Pre-B cell-enhancing factor,Visfatin |
| 2 | C, D (A, B) | 2-[(2-fluorophenyl)amino]-6-propylpyrimidin-4(3H)-one | non-polymer | 247.3 | 2 | Chemie (AQ1) | |||
| 3 | E, F (A, B) | water | water | 18.0 | 629 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 111189.9 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 494.5 | |
| All* | Total formula weight | 111684.4 |
