5WHA
KRas G12V, bound to GDP and miniprotein 225-11
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D, G, J (A, D, G, J) | GTPase KRas | polymer | 170 | 19154.6 | 4 | UniProt (P01116) Pfam (PF00071) | Homo sapiens (Human) | K-Ras 2,Ki-Ras,c-K-ras,c-Ki-ras |
| 2 | B, C, E, F, H... (B, C, E, F, H...) | miniprotein 225-11 | polymer | 35 | 3997.4 | 8 | synthetic construct | ||
| 3 | AA, M, Q, U (J, A, D, G) | MAGNESIUM ION | non-polymer | 24.3 | 4 | Chemie (MG) | |||
| 4 | BA, N, R, V (J, A, D, G) | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 4 | Chemie (GDP) | |||
| 5 | O, P, S, T, W... (A, D, G, I) | CALCIUM ION | non-polymer | 40.1 | 8 | Chemie (CA) | |||
| 6 | CA, DA, EA, FA, GA... (A, B, C, D, E...) | water | water | 18.0 | 180 | Chemie (HOH) |
Sequence modifications
A, D, G, J: 1 - 166 (UniProt: P01116)
| PDB | External Database | Details |
|---|---|---|
| Gly -3 | - | expression tag |
| Gly -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Gly 0 | - | expression tag |
| Val 12 | Gly 12 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 108597.4 | |
| Non-Polymers* | Number of molecules | 16 |
| Total formula weight | 2190.6 | |
| All* | Total formula weight | 110788.1 |
