5WHA
KRas G12V, bound to GDP and miniprotein 225-11
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D, G, J (A, D, G, J) | GTPase KRas | polymer | 170 | 19154.6 | 4 | UniProt (P01116) Pfam (PF00071) | Homo sapiens (Human) | K-Ras 2,Ki-Ras,c-K-ras,c-Ki-ras |
| 2 | B, C, E, F, H... (B, C, E, F, H...) | miniprotein 225-11 | polymer | 35 | 3997.4 | 8 | synthetic construct | ||
| 3 | AA, M, Q, U (J, A, D, G) | MAGNESIUM ION | non-polymer | 24.3 | 4 | Chemie (MG) PubChem (888) | |||
| 4 | BA, N, R, V (J, A, D, G) | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 4 | Chemie (GDP) PubChem (136073927) PubChem (135398619) PubChem (135402030) PubChem (135431654) PubChem (135566337) PubChem (135760556) PubChem (136026707) PubChem (136053418) PubChem (136663964) PubChem (136664748) PubChem (136759848) PubChem (136759849) PubChem (136759850) PubChem (136836636) PubChem (136847074) PubChem (172898537) | |||
| 5 | O, P, S, T, W... (A, D, G, I) | CALCIUM ION | non-polymer | 40.1 | 8 | Chemie (CA) PubChem (271) | |||
| 6 | CA, DA, EA, FA, GA... (A, B, C, D, E...) | water | water | 18.0 | 180 | Chemie (HOH) |
Sequence modifications
A, D, G, J: 1 - 166 (UniProt: P01116)
| PDB | External Database | Details |
|---|---|---|
| Gly -3 | - | expression tag |
| Gly -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Gly 0 | - | expression tag |
| Val 12 | Gly 12 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 108597.4 | |
| Non-Polymers* | Number of molecules | 16 |
| Total formula weight | 2190.6 | |
| All* | Total formula weight | 110788.1 |
