5WH6
Crystal structure of PDE4D2 in complex with inhibitor (S_Zl-n-91)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | polymer | 507 | 57859.5 | 2 | UniProt (Q08499) Pfam (PF18100) Pfam (PF00233) | Homo sapiens (Human) | DPDE3,PDE43 |
| 2 | C, G (A, B) | 1-[4-(difluoromethoxy)-3-{[(3S)-oxolan-3-yl]oxy}phenyl]-3-methylbutan-1-one | non-polymer | 314.3 | 2 | Chemie (AKJ) | |||
| 3 | D, H (A, B) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 4 | E, F, I (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 3 | Chemie (MG) | |||
| 5 | J, K (A, B) | water | water | 18.0 | 384 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 115719.0 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 832.4 | |
| All* | Total formula weight | 116551.4 |
