5WFV
Kelch domain of human Keap1 bound to Nrf2 ETGE peptide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Kelch-like ECH-associated protein 1 | polymer | 336 | 36899.2 | 2 | UniProt (Q14145) Pfam (PF01344) | Homo sapiens (Human) | Cytosolic inhibitor of Nrf2,INrf2,Kelch-like protein 19 |
| 2 | C (P) | Nrf2 ETGE peptide | polymer | 9 | 1052.1 | 1 | UniProt (by SIFTS) (Q16236) | Homo sapiens | |
| 3 | D (B) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 4 | E, F, G (A, B, P) | water | water | 18.0 | 115 | Chemie (HOH) |
Sequence modifications
A, B: 320 - 612 (UniProt: Q14145)
| PDB | External Database | Details |
|---|---|---|
| Met 289 | - | initiating methionine |
| Gly 290 | - | expression tag |
| Ser 291 | - | expression tag |
| Ser 292 | - | expression tag |
| His 293 | - | expression tag |
| His 294 | - | expression tag |
| His 295 | - | expression tag |
| His 296 | - | expression tag |
| His 297 | - | expression tag |
| His 298 | - | expression tag |
| Ser 299 | - | expression tag |
| Ser 300 | - | expression tag |
| Gly 301 | - | expression tag |
| Gly 302 | - | expression tag |
| Glu 303 | - | expression tag |
| Asn 304 | - | expression tag |
| Leu 305 | - | expression tag |
| Tyr 306 | - | expression tag |
| Phe 307 | - | expression tag |
| Gln 308 | - | expression tag |
| Gly 309 | - | expression tag |
| His 310 | - | expression tag |
| Met 311 | - | expression tag |
| Lys 312 | - | expression tag |
| Pro 313 | - | expression tag |
| Thr 314 | - | expression tag |
| Gln 315 | - | expression tag |
| Val 316 | - | expression tag |
| Met 317 | - | expression tag |
| Pro 318 | - | expression tag |
| Ser 319 | - | expression tag |
| Ala 540 | Glu 540 | engineered mutation |
| Ala 542 | Glu 542 | engineered mutation |
| Ser 613 | - | expression tag |
| Arg 614 | - | expression tag |
| Lys 615 | - | expression tag |
| Gln 616 | - | expression tag |
| Ile 617 | - | expression tag |
| Asp 618 | - | expression tag |
| Gln 619 | - | expression tag |
| Gln 620 | - | expression tag |
| Asn 621 | - | expression tag |
| Ser 622 | - | expression tag |
| Thr 623 | - | expression tag |
| Ser 624 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 74850.4 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 96.1 | |
| All* | Total formula weight | 74946.5 |
