5WDM
An ultra-stable single-chain insulin analog resists thermal inactivation and exhibits biological signaling duration equivalent to the native protein
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | Single-chain insulin analog | polymer | 57 | 6529.3 | 6 | UniProt (A6XGL2) Pfam (PF00049) UniProt (by SIFTS) (P01308) | Homo sapiens |
Sequence modifications
A, B, C, D, E, F: 1 - 57 (UniProt: A6XGL2)
| PDB | External Database | Details |
|---|---|---|
| Glu 29 | Lys 53 | conflict |
| - | Arg 55 | deletion |
| - | Arg 56 | deletion |
| - | Glu 57 | deletion |
| - | Ala 58 | deletion |
| - | Glu 59 | deletion |
| - | Asp 60 | deletion |
| - | Leu 61 | deletion |
| - | Gln 62 | deletion |
| - | Gly 63 | deletion |
| - | Ser 64 | deletion |
| - | Leu 65 | deletion |
| - | Gln 66 | deletion |
| - | Pro 67 | deletion |
| - | Leu 68 | deletion |
| - | Ala 69 | deletion |
| - | Leu 70 | deletion |
| - | Glu 71 | deletion |
| Glu 31 | Gly 72 | conflict |
| Glu 32 | Ser 73 | conflict |
| Gly 33 | Leu 74 | conflict |
| Pro 34 | Gln 75 | conflict |
| Arg 35 | Lys 76 | conflict |
| His 44 | Thr 85 | conflict |
| Glu 50 | Tyr 91 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 39176.0 | |
| All* | Total formula weight | 39176.0 |
