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5WCG

SET and MYND Domain Containing protein 2

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
N-lysine methyltransferase SMYD2polymer43349832.21UniProt (Q9NRG4)
Pfam (PF00856)
Pfam (PF01753)
Homo sapiens (Human)HSKM-B,Histone methyltransferase SMYD2,Lysine N-methyltransferase 3C,SET and MYND domain-containing protein 2
2B, C, D
(A)
ZINC IONnon-polymer65.43Chemie (ZN)
3E
(A)
[3-(6-amino-2-methyl-9H-purin-9-yl)azetidin-1-yl]{5-[(4-cycloheptylpiperazin-1-yl)methyl]-1-methyl-1H-pyrazol-3-yl}methanonenon-polymer506.61Chemie (A4M)
4F
(A)
DIMETHYL SULFOXIDEnon-polymer78.11Chemie (DMS)
5G
(A)
2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOLnon-polymer122.11Chemie (TRS)
6H, I, J, K, L
(A)
UNKNOWN ATOM OR IONnon-polymer5Chemie (UNX)
7M
(A)
waterwater18.0185Chemie (HOH)
Sequence modifications
A: 1 - 433 (UniProt: Q9NRG4)
PDBExternal DatabaseDetails
Glu 165Gly 165conflict
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight49832.2
Non-Polymers*Number of molecules11
Total formula weight903.1
All*Total formula weight50735.3
*Water molecules are not included.

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PDB entries from 2025-07-23

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