5WB9
Crystal structure of CD4 binding site antibody N60P23 in complex with HIV-1 clade A/E strain 93TH057 gp120 core
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | G | clade A/E 93TH057 HIV-1 gp120 core | polymer | 353 | 39160.4 | 1 | UniProt (A0A0M3KKW9) Pfam (PF00516) In PDB | Human immunodeficiency virus 1 | |
| 2 | H | N60P23 Fab heavy chain | polymer | 227 | 24573.6 | 1 | Homo sapiens | ||
| 3 | L | N60P23 Fab light chain | polymer | 208 | 23011.6 | 1 | Homo sapiens | ||
| 4 | G | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 8 | Chemie (NAG) | |||
| 5 | G | (4S)-2-METHYL-2,4-PENTANEDIOL | non-polymer | 118.2 | 1 | Chemie (MPD) | |||
| 6 | G | 3[N-MORPHOLINO]PROPANE SULFONIC ACID | non-polymer | 209.3 | 1 | Chemie (MPO) | |||
| 7 | water | water | 18.0 | 222 | Chemie (HOH) |
Sequence modifications
G: 44 - 492 (UniProt: A0A0M3KKW9)
| PDB | External Database | Details |
|---|---|---|
| Ser 375 | His 242 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 86745.6 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 2097.1 | |
| All* | Total formula weight | 88842.7 |
