5WA1

CHMP4C A232T in complex with ALIX BRO1

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Programmed cell death 6-interacting protein	polymer	379	42636.7	1	UniProt (Q8WUM4) Pfam (PF03097)	Homo sapiens (Human)	ALIX, PDCD6-interacting protein, ALG-2-interacting protein 1, ALG-2-interacting protein X, Hp95
2	B (B)	Charged multivesicular body protein 4c	polymer	18	2121.2	1	UniProt (Q96CF2)	Homo sapiens	Chromatin-modifying protein 4c, CHMP4c, SNF7 homolog associated with Alix 3, SNF7-3, hSnf7-3, Vacuolar protein sorting-associated protein 32-3, hVps32-3
3	C, D (A, B)	water	water		18.0	92	Chemie (HOH)

Sequence modifications

A: 1 - 358 (UniProt: Q8WUM4)

PDB	External Database	Details
Met -20	-	expression tag
His -19	-	expression tag
His -18	-	expression tag
His -17	-	expression tag
His -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
Ser -9	-	expression tag
Gly -8	-	expression tag
Gln -7	-	expression tag
Asn -6	-	expression tag
Leu -5	-	expression tag
Tyr -4	-	expression tag
Phe -3	-	expression tag
Gln -2	-	expression tag
Gly -1	-	expression tag
His 0	-	expression tag

B: 216 - 233 (UniProt: Q96CF2)

PDB	External Database	Details
Thr 232	Ala 232	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	44757.9
All*	Total formula weight	44757.9

*Water molecules are not included.