5W9I
MERS S ectodomain trimer in complex with variable domain of neutralizing antibody G4
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, E, F, I... | Spike glycoprotein | polymer | 1329 | 146326.0 | 6 | UniProt (W5ZZF5) Pfam (PF16451) Pfam (PF09408) Pfam (PF19209) Pfam (PF01601) UniProt (by SIFTS) (K9N5Q8) In PDB | Middle East respiratory syndrome-related coronavirus | S protein |
2 | C, G, K | G4 VH | polymer | 233 | 25312.4 | 3 | Mus musculus | ||
3 | D, H, L | G4 VL | polymer | 218 | 23867.4 | 3 | Mus musculus | ||
4 | a, b, c, d, e... | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 21 | In PDB GlyTouCan (G42666HT) | |||
5 | J, A, B, E, F... | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 21 | Chemie (NAG) |
Sequence modifications
A, B, E, F, I, J: 1 - 1291 (UniProt: W5ZZF5)
PDB | External Database | Details |
---|---|---|
Phe 506 | Leu 506 | conflict |
Ala 748 | Arg 748 | conflict |
Gly 751 | Arg 751 | conflict |
Pro 1060 | Val 1060 | engineered mutation |
Pro 1061 | Leu 1061 | engineered mutation |
Gly 1292 | - | expression tag |
Ser 1293 | - | expression tag |
Gly 1294 | - | expression tag |
Tyr 1295 | - | expression tag |
Ile 1296 | - | expression tag |
Pro 1297 | - | expression tag |
Glu 1298 | - | expression tag |
Ala 1299 | - | expression tag |
Pro 1300 | - | expression tag |
Arg 1301 | - | expression tag |
Asp 1302 | - | expression tag |
Gly 1303 | - | expression tag |
Gln 1304 | - | expression tag |
Ala 1305 | - | expression tag |
Tyr 1306 | - | expression tag |
Val 1307 | - | expression tag |
Arg 1308 | - | expression tag |
Lys 1309 | - | expression tag |
Asp 1310 | - | expression tag |
Gly 1311 | - | expression tag |
Glu 1312 | - | expression tag |
Trp 1313 | - | expression tag |
Val 1314 | - | expression tag |
Leu 1315 | - | expression tag |
Leu 1316 | - | expression tag |
Ser 1317 | - | expression tag |
Thr 1318 | - | expression tag |
Phe 1319 | - | expression tag |
Leu 1320 | - | expression tag |
Gly 1321 | - | expression tag |
Arg 1322 | - | expression tag |
Ser 1323 | - | expression tag |
Leu 1324 | - | expression tag |
Glu 1325 | - | expression tag |
Val 1326 | - | expression tag |
Leu 1327 | - | expression tag |
Phe 1328 | - | expression tag |
Gln 1329 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 12 |
Total formula weight | 1025495.0 | |
Branched | Number of molecules | 21 |
Total formula weight | 8912.4 | |
Non-Polymers* | Number of molecules | 21 |
Total formula weight | 4645.4 | |
All* | Total formula weight | 1039052.8 |