5W89
Crystal structure of human Mcl-1 in complex with modified Bim BH3 peptide SAH-MS1-18
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Induced myeloid leukemia cell differentiation protein Mcl-1 | polymer | 151 | 17249.7 | 1 | UniProt (Q07820) Pfam (PF00452) | Homo sapiens (Human) | Bcl-2-like protein 3,Bcl2-L-3,Bcl-2-related protein EAT/mcl1,mcl1/EAT |
| 2 | B (B) | modified Bim BH3 peptide SAH-MS1-18 | polymer | 22 | 2497.9 | 1 | Homo sapiens | ||
| 3 | C, D (A) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 4 | E, F (A, B) | water | water | 18.0 | 124 | Chemie (HOH) |
Sequence modifications
A: 172 - 321 (UniProt: Q07820)
| PDB | External Database | Details |
|---|---|---|
| Gly 171 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 19747.6 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 130.8 | |
| All* | Total formula weight | 19878.5 |
