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5W87

Crystal structure of the C-terminal lobe of the human HERC6 HECT domain

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Probable E3 ubiquitin-protein ligase HERC6polymer12114382.32UniProt (Q8IVU3)
Pfam (PF00632)
Homo sapiens (Human)HECT domain and RCC1-like domain-containing protein 6,HECT-type E3 ubiquitin transferase HERC6
2C
(A)
PHOSPHATE IONnon-polymer95.01Chemie (PO4)
3D, E
(A, B)
waterwater18.035Chemie (HOH)
Sequence modifications
A, B: 902 - 1022 (UniProt: Q8IVU3)
PDBExternal DatabaseDetails
Ser 970Cys 970engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight28764.6
Non-Polymers*Number of molecules1
Total formula weight95.0
All*Total formula weight28859.6
*Water molecules are not included.

246031

PDB entries from 2025-12-10

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