5W7F

Murine acyloxyacyl hydrolase (AOAH), S262A mutant, with lipid A

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Acyloxyacyl hydrolase	polymer	562	64034.2	2	UniProt (O35298) Pfam (PF03489) Pfam (PF00657)	Mus musculus (Mouse)
2	C, D, E, I, J... (A, B)	CALCIUM ION	non-polymer		40.1	6	Chemie (CA)
3	F, L (A, B)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	2	Chemie (NAG)
4	G, M (A, B)	3-HYDROXY-TETRADECANOIC ACID	non-polymer		244.4	2	Chemie (FTT)
5	H, N (A, B)	LAURIC ACID	non-polymer		200.3	2	Chemie (DAO)
6	O (B)	2-amino-2-deoxy-beta-D-glucopyranose	non-polymer		179.2	1	Chemie (GCS)
7	P, Q (A, B)	water	water		18.0	19	Chemie (HOH)

Sequence modifications

A, B: 23 - 574 (UniProt: O35298)

PDB	External Database	Details
Asp 13	-	expression tag
Arg 14	-	expression tag
His 15	-	expression tag
His 16	-	expression tag
His 17	-	expression tag
His 18	-	expression tag
His 19	-	expression tag
His 20	-	expression tag
Lys 21	-	expression tag
Leu 22	-	expression tag
Arg 152	Pro 152	conflict
Val 184	Ile 184	conflict
Ala 262	Ser 262	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	128068.4
Non-Polymers*	Number of molecules	13
	Total formula weight	1751.4
All*	Total formula weight	129819.8

*Water molecules are not included.