5W4B
The crystal structure of human S-adenosylhomocysteine hydrolase (AHCY) bound to benzothiazole inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | Adenosylhomocysteinase | polymer | 429 | 47439.6 | 6 | UniProt (P23526) Pfam (PF05221) Pfam (PF00670) | Homo sapiens (Human) | AdoHcyase, S-adenosyl-L-homocysteine hydrolase |
| 2 | G, I, K, M, O... (A, B, C, D, E...) | NICOTINAMIDE-ADENINE-DINUCLEOTIDE | non-polymer | 663.4 | 6 | Chemie (NAD) | |||
| 3 | H, J, L, N, P... (A, B, C, D, E...) | 4-[(2,5-dioxo-2,5-dihydro-1H-imidazol-1-yl)methyl]-N-[2-(morpholin-4-yl)-1,3-benzothiazol-6-yl]benzamide | non-polymer | 449.5 | 6 | Chemie (9W4) | |||
| 4 | Q (E) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 5 | T, U, V, W, X... (A, B, C, D, E...) | water | water | 18.0 | 1249 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 284637.6 | |
| Non-Polymers* | Number of molecules | 13 |
| Total formula weight | 6739.5 | |
| All* | Total formula weight | 291377.1 |
