5W49
The crystal structure of human S-adenosylhomocysteine hydrolase (AHCY) bound to oxadiazole inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Adenosylhomocysteinase | polymer | 429 | 47439.6 | 2 | UniProt (P23526) Pfam (PF05221) Pfam (PF00670) | Homo sapiens (Human) | AdoHcyase, S-adenosyl-L-homocysteine hydrolase |
| 2 | C, L (A, B) | NICOTINAMIDE-ADENINE-DINUCLEOTIDE | non-polymer | 663.4 | 2 | Chemie (NAD) | |||
| 3 | D, E, F, G, H... (A, B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 14 | Chemie (EDO) | |||
| 4 | J, T (A, B) | (4-amino-1,2,5-oxadiazol-3-yl)[(3R)-3-{4-[(3-methoxyphenyl)amino]-6-methylpyridin-2-yl}pyrrolidin-1-yl]methanone | non-polymer | 394.4 | 2 | Chemie (9W1) | |||
| 5 | U, V (A, B) | water | water | 18.0 | 441 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 94879.2 | |
| Non-Polymers* | Number of molecules | 18 |
| Total formula weight | 2984.7 | |
| All* | Total formula weight | 97863.9 |
