5W42
Crystal structure of human monoclonal antibody H3v-47 in complex with influenza virus hemagglutinin from A/Minnesota/11/2010 (H3N2)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Hemagglutinin | polymer | 329 | 36788.2 | 1 | UniProt (I0AXC3) Pfam (PF00509) | Influenza A virus (A/swine/Minnesota/A01134337/2010(H3N2)) | |
| 2 | B (B) | Hemagglutinin | polymer | 174 | 20055.3 | 1 | UniProt (I0AXC3) Pfam (PF00509) | Influenza A virus | |
| 3 | C (H) | Fab H3v-47 heavy chain | polymer | 236 | 25227.2 | 1 | UniProt (Q6N089) Pfam (PF07686) Pfam (PF07654) | Homo sapiens (Human) | |
| 4 | D (L) | Fab H3v-47 light chain | polymer | 214 | 23256.7 | 1 | UniProt (Q8TCD0) Pfam (PF07686) Pfam (PF07654) | Homo sapiens (Human) | |
| 5 | E, I (C, G) | alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 910.8 | 2 | In PDB GlyTouCan (G22768VO) | |||
| 6 | F (D) | alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 748.7 | 1 | In PDB GlyTouCan (G81315DD) | |||
| 7 | G (E) | alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1073.0 | 1 | In PDB GlyTouCan (G36544AC) | |||
| 8 | H (F) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 1 | In PDB GlyTouCan (G15407YE) | |||
| 9 | J (I) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) | |||
| 10 | K, L (A) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) | |||
| 11 | M (H) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) |
Sequence modifications
H: 1 - 108 (PDB: 5W42)
H: 109 - 216 (UniProt: Q6N089)
L: 1 - 104 (PDB: 5W42)
L: 105 - 213 (UniProt: Q8TCD0)
H: 109 - 216 (UniProt: Q6N089)
| PDB | External Database | Details |
|---|---|---|
| His 217 | - | expression tag |
| His 218 | - | expression tag |
| His 219 | - | expression tag |
| His 220 | - | expression tag |
| His 221 | - | expression tag |
| His 222 | - | expression tag |
L: 105 - 213 (UniProt: Q8TCD0)
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 105327.4 | |
| Branched | Number of molecules | 6 |
| Total formula weight | 4654.2 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 507.8 | |
| All* | Total formula weight | 110489.5 |
