5W1O

Crystal Structure of HPV16 L1 Pentamer Bound to Heparin Oligosaccharides

This is a non-PDB format compatible entry.

Replaces:  3OAE

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E (A, B, C, D, E)	Major capsid protein L1	polymer	427	47549.5	5	UniProt (Q81007)	Human papillomavirus	Late major capsid protein L1
2	F, H, I, J, K... (F, H, I, J, K...)	2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-alpha-D-glucopyranose	branched		500.4	10	In PDB GlyTouCan (G75183WV)
3	G (G)	2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-alpha-D-glucopyranose	branched		1465.2	1	In PDB GlyTouCan (G29325GF)
4	Q, R, S, T, U (A, B, C, D, E)	water	water		18.0	147	Chemie (HOH)

Sequence modifications

A, B, C, D, E: 21 - 403 (UniProt: Q81007)

PDB	External Database	Details
Ala 20	-	expression tag

A, B, C, D, E: 438 - 474 (UniProt: Q81007)

PDB	External Database	Details
Gly 432	-	linker
Gly 433	-	linker
Gly 434	-	linker
Ser 435	-	linker
Gly 436	-	linker
Ala 437	-	linker

Contents of the asymmetric unit

Polymers	Number of chains	5
	Total formula weight	237747.7
Branched	Number of molecules	11
	Total formula weight	6469.3
All*	Total formula weight	244217.0

*Water molecules are not included.