5W0W
Crystal structure of Protein Phosphatase 2A bound to TIPRL
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, D, G, J | Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform | polymer | 585 | 65701.6 | 4 | UniProt (P30153) Pfam (PF02985) In PDB | Homo sapiens (Human) | Medium tumor antigen-associated 61 kDa protein,PP2A subunit A isoform PR65-alpha,PP2A subunit A isoform R1-alpha |
2 | B, E, H, K | TIP41-like protein | polymer | 251 | 29044.3 | 4 | UniProt (Q8BH58) Pfam (PF04176) In PDB | Mus musculus (Mouse) | |
3 | C, F, I, L | Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform | polymer | 311 | 35780.3 | 4 | UniProt (P67775) Pfam (PF00149) In PDB | Homo sapiens (Human) | PP2A-alpha,Replication protein C,RP-C |
4 | C, F, I, L | MANGANESE (II) ION | non-polymer | 54.9 | 4 | Chemie (MN) |
Sequence modifications
A, D, G, J: 9 - 589 (UniProt: P30153)
B, E, H, K: 12 - 259 (UniProt: Q8BH58)
C, F, I, L: 1 - 309 (UniProt: P67775)
PDB | External Database | Details |
---|---|---|
Gly 5 | - | expression tag |
Ser 6 | - | expression tag |
His 7 | - | expression tag |
Mse 8 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Gly 9 | - | expression tag |
Ser 10 | - | expression tag |
Met 11 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Gly -1 | - | expression tag |
Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 12 |
Total formula weight | 522104.7 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 219.8 | |
All* | Total formula weight | 522324.4 |