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5W0N

Structure of human TUT7 catalytic module (CM) in complex with UMPNPP and U2 RNA

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C
(A, B, C)
Terminal uridylyltransferase 7polymer40346659.13UniProt (Q5VYS8)
Pfam (PF00098)
Pfam (PF22600)
Pfam (PF03828)
Homo sapiens (Human)TUT7, TUTase 7, Zinc finger CCHC domain-containing protein 6
2D, J, O
(A, B, C)
MAGNESIUM IONnon-polymer24.33Chemie (MG)
3E, K, P
(A, B, C)
5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]uridinenon-polymer483.23Chemie (2KH)
4F, L, Q
(A, B, C)
[(2R,3S,4R,5R)-5-(2,4-DIOXO-3,4-DIHYDROPYRIMIDIN-1(2H)-YL)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL]METHYL (2R,3S,4R,5R)-5-(2,4-DIOXO-3,4-DIHYDROPYRIMIDIN-1(2H)-YL)-4-HYDROXY-2-(HYDROXYMETHYL)TETRAHYDROFURAN-3-YL HYDROGEN (S)-PHOSPHATEnon-polymer550.43Chemie (UPU)
5G, M
(A, B)
ZINC IONnon-polymer65.42Chemie (ZN)
6H, N, R
(A, B, C)
IODIDE IONnon-polymer126.93Chemie (IOD)
7I
(A)
SULFATE IONnon-polymer96.11Chemie (SO4)
8S, T, U
(A, B, C)
waterwater18.0218Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight139977.4
Non-Polymers*Number of molecules15
Total formula weight3781.1
All*Total formula weight143758.5
*Water molecules are not included.

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PDB entries from 2024-10-30

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