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SummaryStructural detailsExperimental detailsFunctional detailsSequence NeighborHistoryDownloads

5VYC

Crystal structure of the human 40S ribosomal subunit in complex with DENR-MCT-1.

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1T1, T2, T3, T4, T5...40S ribosomal protein S19polymer14516091.66UniProt (P39019)
Pfam (PF01090)
In PDB		Homo sapiens (Human)Small ribosomal subunit protein eS19
2U1, U2, U3, U4, U5...40S ribosomal protein S20polymer11913398.86UniProt (P60866)
Pfam (PF00338)
In PDB		Homo sapiens (Human)Small ribosomal subunit protein uS10
3V1, V2, V3, V4, V5...40S ribosomal protein S21polymer839124.46UniProt (P63220)
Pfam (PF01249)
In PDB		Homo sapiens (Human)Small ribosomal subunit protein eS21
4X1, X2, X3, X4, X5...40S ribosomal protein S23polymer14315844.76UniProt (P62266)
Pfam (PF00164)
In PDB		Homo sapiens (Human)Small ribosomal subunit protein uS12
5a1, a2, a3, a4, a5...40S ribosomal protein S26polymer11513047.56UniProt (P62854)
Pfam (PF01283)
In PDB		Homo sapiens (Human)Small ribosomal subunit protein eS26
6c1, c2, c3, c4, c5...40S ribosomal protein S28polymer697855.16UniProt (P62857)
Pfam (PF01200)
In PDB		Homo sapiens (Human)Small ribosomal subunit protein eS28
7d1, d2, d3, d4, d5...40S ribosomal protein S29polymer566690.86UniProt (P62273)
Pfam (PF00253)
In PDB		Homo sapiens (Human)Small ribosomal subunit protein uS14
8f1, f2, f3, f4, f5...Ribosomal protein S27apolymer15617944.06UniProt (Q5RKT7)
Pfam (PF00240)
Pfam (PF01599)
In PDB		Homo sapiens (Human)
9g1, g2, g3, g4, g5...Receptor of activated protein C kinase 1polymer31735115.76UniProt (P63244)
Pfam (PF00400)
In PDB		Homo sapiens (Human)Cell proliferation-inducing gene 21 protein,Guanine nucleotide-binding protein subunit beta-2-like 1,Guanine nucleotide-binding protein subunit beta-like protein 12.3,Human lung cancer oncogene 7 protein,HLC-7,Receptor for activated C kinase,Small ribosomal subunit protein RACK1
10C1, C2, C3, C4, C5...40S ribosomal protein S2polymer29331376.56UniProt (P15880)
Pfam (PF00333)
Pfam (PF03719)
In PDB		Homo sapiens (Human)40S ribosomal protein S4,Protein LLRep3,Small ribosomal subunit protein uS5
11G1, G2, G3, G4, G5...40S ribosomal protein S6polymer24928751.96UniProt (P62753)
Pfam (PF01092)
In PDB		Homo sapiens (Human)Phosphoprotein NP33,Small ribosomal subunit protein eS6
12J1, J2, J3, J4, J5...40S ribosomal protein S9polymer19422641.66UniProt (P46781)
Pfam (PF00163)
Pfam (PF01479)
In PDB		Homo sapiens (Human)Small ribosomal subunit protein uS4
13M1, M2, M3, M4, M5...40S ribosomal protein S12polymer13214539.06UniProt (P25398)
Pfam (PF01248)
In PDB		Homo sapiens (Human)Small ribosomal subunit protein eS12
14N1, N2, N3, N4, N5...40S ribosomal protein S13polymer15117259.46UniProt (P62277)
Pfam (PF08069)
Pfam (PF00312)
In PDB		Homo sapiens (Human)Small ribosomal subunit protein uS15
15O1, O2, O3, O4, O5...40S ribosomal protein S14polymer15116302.86UniProt (P62263)
Pfam (PF00411)
In PDB		Homo sapiens (Human)Small ribosomal subunit protein uS11
16W1, W2, W3, W4, W5...40S ribosomal protein S15apolymer13014865.66UniProt (P62244)
Pfam (PF00410)
In PDB		Homo sapiens (Human)Small ribosomal subunit protein uS8
17Y1, Y2, Y3, Y4, Y5...40S ribosomal protein S24polymer13315463.36UniProt (P62847)
Pfam (PF01282)
In PDB		Homo sapiens (Human)Small ribosomal subunit protein eS24
18Z1, Z2, Z3, Z4, Z5...40S ribosomal protein S25polymer12513776.26UniProt (P62851)
Pfam (PF03297)
In PDB		Homo sapiens (Human)Small ribosomal subunit protein eS25
19b1, b2, b3, b4, b5...40S ribosomal protein S27polymer849480.26UniProt (P42677)
Pfam (PF01667)
In PDB		Homo sapiens (Human)Metallopan-stimulin 1,MPS-1,Small ribosomal subunit protein eS27
20e1, e2, e3, e4, e5...40S ribosomal protein S30polymer13314415.76UniProt (E9PR30)
Pfam (PF04758)
In PDB		Homo sapiens (Human)
21i1, i2, i3, i4, i5...Human 18S ribosomal RNApolymer1869602752.96GenBank (36162)Homo sapiens
22A1, A2, A3, A4, A5...40S ribosomal protein SApolymer29532883.96UniProt (P08865)
Pfam (PF00318)
Pfam (PF16122)
In PDB		Homo sapiens (Human)37 kDa laminin receptor precursor,37LRP,37/67 kDa laminin receptor,LRP/LR,67 kDa laminin receptor,67LR,Colon carcinoma laminin-binding protein,Laminin receptor 1,LamR,Laminin-binding protein precursor p40,LBP/p40,Multidrug resistance-associated protein MGr1-Ag,NEM/1CHD4,Small ribosomal subunit protein uS2
23B1, B2, B3, B4, B5...40S ribosomal protein S3apolymer26430002.16UniProt (P61247)
Pfam (PF01015)
In PDB		Homo sapiens (Human)Small ribosomal subunit protein eS1,v-fos transformation effector protein,Fte-1
24D1, D2, D3, D4, D5...40S ribosomal protein S3polymer24326729.46UniProt (P23396)
Pfam (PF07650)
Pfam (PF00189)
In PDB		Homo sapiens (Human)Small ribosomal subunit protein uS3
25E1, E2, E3, E4, E5...40S ribosomal protein S4, X isoformpolymer26329654.96UniProt (P62701)
Pfam (PF00900)
Pfam (PF00467)
Pfam (PF16121)
Pfam (PF08071)
In PDB		Homo sapiens (Human)SCR10,Single copy abundant mRNA protein,Small ribosomal subunit protein eS4
26F1, F2, F3, F4, F5...40S ribosomal protein S5polymer20422913.56UniProt (P46782)
Pfam (PF00177)
In PDB		Homo sapiens (Human)Small ribosomal subunit protein uS7
27H1, H2, H3, H4, H5...40S ribosomal protein S7polymer19422168.96UniProt (P62081)
Pfam (PF01251)
In PDB		Homo sapiens (Human)Small ribosomal subunit protein eS7
28I1, I2, I3, I4, I5...40S ribosomal protein S8polymer20824263.46UniProt (P62241)
Pfam (PF01201)
In PDB		Homo sapiens (Human)Small ribosomal subunit protein eS8
29K1, K2, K3, K4, K5...40S ribosomal protein S10polymer16518933.86UniProt (P46783)
Pfam (PF03501)
In PDB		Homo sapiens (Human)Small ribosomal subunit protein eS10
30L1, L2, L3, L4, L5...40S ribosomal protein S11polymer15818468.86UniProt (P62280)
Pfam (PF16205)
Pfam (PF00366)
In PDB		Homo sapiens (Human)Small ribosomal subunit protein uS17
31P1, P2, P3, P4, P5...40S ribosomal protein S15polymer14517076.26UniProt (P62841)
Pfam (PF00203)
In PDB		Homo sapiens (Human)RIG protein,Small ribosomal subunit protein uS19
32Q1, Q2, Q3, Q4, Q5...40S ribosomal protein S16polymer14616477.46UniProt (P62249)
Pfam (PF00380)
In PDB		Homo sapiens (Human)Small ribosomal subunit protein uS9
33R1, R2, R3, R4, R5...40S ribosomal protein S17polymer13515578.26UniProt (P08708)
Pfam (PF00833)
In PDB		Homo sapiens (Human)Small ribosomal subunit protein eS17
34S1, S2, S3, S4, S5...40S ribosomal protein S18polymer15217759.86UniProt (P62269)
Pfam (PF00416)
In PDB		Homo sapiens (Human)Ke-3,Ke3,Small ribosomal subunit protein uS13
35j1, j2, j3, j4, j5...60S ribosomal protein L41polymer253473.56UniProt (P62945)
Pfam (PF05162)
In PDB		Homo sapiens (Human)HG12,Large ribosomal subunit protein eL41
36k1, k2, k3, k4, k5...Malignant T-cell-amplified sequence 1polymer18120585.36UniProt (Q9ULC4)
Pfam (PF17832)
Pfam (PF01472)
In PDB		Homo sapiens (Human)MCT-1,Multiple copies T-cell malignancies
37l1, l2, l3, l4, l5...Density-regulated proteinpolymer19822124.06UniProt (O43583)
Pfam (PF21023)
Pfam (PF01253)
In PDB		Homo sapiens (Human)DRP,Protein DRP1,Smooth muscle cell-associated protein 3,SMAP-3
38f1, f2, f3, f4, f5...ZINC IONnon-polymer65.46Chemie (ZN)
Sequence modifications
e1, e2, e3, e4, e5, e6: -73 - 59 (UniProt: E9PR30)
PDBExternal DatabaseDetails
Ala -48-insertion
His -47-insertion
Val -46-insertion
Ala -45-insertion
Ser -44-insertion
Leu -43-insertion
Glu -42-insertion
Gly -41-insertion
Ile -40-insertion
Ala -39-insertion
Pro -38-insertion
Glu -37-insertion
Asp -36-insertion
Gln -35-insertion
Val -34-insertion
Val -33-insertion
Leu -32-insertion
Leu -31-insertion
Ala -30-insertion
Gly -29-insertion
Ala -28-insertion
Pro -27-insertion
Leu -26-insertion
Glu -25-insertion
Asp -24-insertion
Glu -23-insertion
Ala -22-insertion
Thr -21-insertion
Leu -20-insertion
Gly -19-insertion
Gln -18-insertion
Cys -17-insertion
Gly -16-insertion
Val -15-insertion
Glu -14-insertion
i1, i2, i3, i4, i5, i6: 1 - 1869 (GenBank: 36162)
PDBExternal DatabaseDetails
C 582U 582conflict
C 583A 583conflict
G 584A 584conflict
A 798G 798conflict
U 1095C 1095conflict
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains222
Total formula weight7654982.7
Non-Polymers*Number of molecules6
Total formula weight392.5
All*Total formula weight7655375.2
*Water molecules are not included.

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PDB entries from 2024-07-24

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