5VWX

Bak core latch dimer in complex with Bim-h0-h3Glt

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C (A, C)	Bcl-2 homologous antagonist/killer	polymer	170	19037.3	2	UniProt (Q16611) Pfam (PF00452)	Homo sapiens (Human)	Apoptosis regulator BAK,Bcl-2-like protein 7,Bcl2-L-7
2	B, D (B, D)	Bcl-2-like protein 11	polymer	23	2785.1	2	UniProt (O43521) Pfam (PF08945)	Homo sapiens	Bcl2-L-11,Bcl2-interacting mediator of cell death
3	E, F, G (B, C)	1,2-ETHANEDIOL	non-polymer		62.1	3	Chemie (EDO)
4	H, I, J, K (A, B, C, D)	water	water		18.0	37	Chemie (HOH)

Sequence modifications

A, C: 23 - 186 (UniProt: Q16611)

PDB	External Database	Details
Gly 17	-	expression tag
Pro 18	-	expression tag
Leu 19	-	expression tag
Gly 20	-	expression tag
Ser 21	-	expression tag
Met 22	-	expression tag
Ser 166	Cys 166	engineered mutation

B, D: 142 - 164 (UniProt: O43521)

PDB	External Database	Details
Ser 142	Met 142	engineered mutation
Ile 144	Pro 144	engineered mutation
Ile 145	Glu 145	engineered mutation
Ser 146	Ile 146	engineered mutation
Arg 147	Trp 147	engineered mutation
Thr 162	Tyr 162	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	43644.8
Non-Polymers*	Number of molecules	3
	Total formula weight	186.2
All*	Total formula weight	43831.0

*Water molecules are not included.