5VU8
TNA polymerase, closed ternary complex
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | DNA polymerase | polymer | 774 | 90130.6 | 1 | UniProt (D0VWU9) Pfam (PF03104) Pfam (PF00136) In PDB | Thermococcus kodakarensis | Kod-RI |
2 | T | DNA template | polymer | 16 | 4898.2 | 1 | synthetic construct | ||
3 | P | DNA/TNA hybrid primer | polymer | 12 | 3642.4 | 1 | synthetic construct | ||
4 | A | [(3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-4-oxidanyl-oxolan-3-yl] [oxidanyl(phosphonooxy)phosphoryl] hydrogen phosphate | non-polymer | 477.2 | 1 | Chemie (9O7) | |||
5 | A, P | MAGNESIUM ION | non-polymer | 24.3 | 3 | Chemie (MG) | |||
6 | water | water | 18.0 | 1 | Chemie (HOH) |
Sequence modifications
A: 1 - 774 (UniProt: D0VWU9)
PDB | External Database | Details |
---|---|---|
Ala 141 | Asp 141 | engineered mutation |
Ala 143 | Glu 143 | engineered mutation |
His 147 | Glu 147 | engineered mutation |
Arg 485 | Ala 485 | engineered mutation |
Lys 584 | Glu 584 | engineered mutation |
Ile 664 | Glu 664 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 3 |
Total formula weight | 98671.2 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 550.1 | |
All* | Total formula weight | 99221.3 |