5VSV

Crystal Structure of Inosine 5'-monophosphate Dehydrogenase from Clostridium perfringens Complexed with IMP and P225

Replaces:  5UZO

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Inosine-5'-monophosphate dehydrogenase	polymer	363	38441.3	4	UniProt (A0A127ELD1) Pfam (PF00478)	Clostridium perfringens	IMPDH,IMPDH
2	E, H, J, L (A, B, C, D)	INOSINIC ACID	non-polymer		348.2	4	Chemie (IMP)
3	F, G, I, K (A, B, C)	{2-chloro-5-[({2-[3-(prop-1-en-2-yl)phenyl]propan-2-yl}carbamoyl)amino]phenoxy}acetic acid	non-polymer		402.9	4	Chemie (8KY)
4	M, N, O, P (A, B, C, D)	water	water		18.0	212	Chemie (HOH)

Sequence modifications

A, B, C, D: 1 - 88 (UniProt: A0A127ELD1)

PDB	External Database	Details
Ser -2	-	expression tag
Asn -1	-	expression tag
Ala 0	-	expression tag

A, B, C, D: 216 - 484 (UniProt: A0A127ELD1)

PDB	External Database	Details
Ser 89	-	linker
Gly 90	-	linker
Gly 91	-	linker

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	153765.1
Non-Polymers*	Number of molecules	8
	Total formula weight	3004.3
All*	Total formula weight	156769.4

*Water molecules are not included.