5VSU

Structure of yeast U6 snRNP with 2'-phosphate terminated U6 RNA

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	U4/U6 snRNA-associated-splicing factor PRP24	polymer	452	51998.8	1	UniProt (P49960) Pfam (PF00076) Pfam (PF16842) Pfam (PF05391)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	U4/U6 snRNP protein
2	B (B)	U6 snRNA-associated Sm-like protein LSm2	polymer	98	11453.2	1	UniProt (P38203) Pfam (PF01423)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	Small nuclear ribonucleoprotein D homolog SNP3
3	C (C)	U6 snRNA-associated Sm-like protein LSm3	polymer	92	10314.6	1	UniProt (P57743) Pfam (PF01423)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	SmX4 protein
4	D (D)	U6 snRNA-associated Sm-like protein LSm4	polymer	96	10902.4	1	UniProt (P40070) Pfam (PF01423)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
5	E (E)	U6 snRNA-associated Sm-like protein LSm5	polymer	96	10708.3	1	UniProt (P40089) Pfam (PF01423)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
6	F (F)	U6 snRNA-associated Sm-like protein LSm6	polymer	88	9550.7	1	UniProt (Q06406) Pfam (PF01423)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
7	G (G)	U6 snRNA-associated Sm-like protein LSm7	polymer	118	13302.4	1	UniProt (P53905) Pfam (PF01423)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
8	H (H)	U6 snRNA-associated Sm-like protein LSm8	polymer	111	12547.5	1	UniProt (P47093) Pfam (PF01423)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
9	I (I)	Saccharomyces cerevisiae strain T8 chromosome XII sequence	polymer	83	26695.7	1	GenBank (1039023528)	Saccharomyces cerevisiae (Baker's yeast)

Sequence modifications

A: 1 - 444 (UniProt: P49960)

PDB	External Database	Details
Leu 445	-	expression tag
Glu 446	-	expression tag
His 447	-	expression tag
His 448	-	expression tag
His 449	-	expression tag
His 450	-	expression tag
His 451	-	expression tag
His 452	-	expression tag

B: 1 - 95 (UniProt: P38203)

PDB	External Database	Details
Met -2	-	initiating methionine
Gly -1	-	expression tag
Ser 0	-	expression tag

C: 1 - 89 (UniProt: P57743)

PDB	External Database	Details
Met -2	-	initiating methionine
Gly -1	-	expression tag
Ser 0	-	expression tag

D: 1 - 93 (UniProt: P40070)

PDB	External Database	Details
Met -2	-	initiating methionine
Gly -1	-	expression tag
Ser 0	-	expression tag

E: 1 - 93 (UniProt: P40089)

PDB	External Database	Details
Met -2	-	initiating methionine
Gly -1	-	expression tag
Ser 0	-	expression tag

F: 1 - 86 (UniProt: Q06406)

PDB	External Database	Details
Gly -1	-	expression tag
Ser 0	-	expression tag

G: 1 - 115 (UniProt: P53905)

PDB	External Database	Details
Met -2	-	initiating methionine
Gly -1	-	expression tag
Ser 0	-	expression tag

H: 1 - 109 (UniProt: P47093)

PDB	External Database	Details
Gly -1	-	expression tag
Ser 0	-	expression tag

I: 30 - 112 (GenBank: 1039023528)

PDB	External Database	Details
G 62	A 365963	conflict

Contents of the asymmetric unit

Polymers	Number of chains	9
	Total formula weight	157473.6
All*	Total formula weight	157473.6

*Water molecules are not included.