5VRZ
Human DNA polymerase beta 8-oxoG:dC extension with dTTP after 60 s
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (T) | DNA (5'-D(*CP*CP*GP*AP*CP*AP*(8OG)P*GP*CP*GP*CP*AP*TP*CP*AP*G)-3') | polymer | 16 | 4909.2 | 1 | synthetic construct | ||
| 2 | B (P) | DNA (5'-D(*CP*TP*GP*AP*TP*GP*CP*GP*CP*CP*T)-3') | polymer | 11 | 3325.2 | 1 | synthetic construct | ||
| 3 | C (D) | DNA (5'-D(P*GP*TP*CP*GP*G)-3') | polymer | 5 | 1536.0 | 1 | synthetic construct | ||
| 4 | D (A) | DNA polymerase beta | polymer | 341 | 39070.5 | 1 | UniProt (P06746) Pfam (PF14716) Pfam (PF10391) Pfam (PF14792) Pfam (PF14791) | Homo sapiens (Human) | |
| 5 | E (P) | THYMIDINE-5'-TRIPHOSPHATE | non-polymer | 482.2 | 1 | Chemie (TTP) | |||
| 6 | F, G, H, I, J (P) | MAGNESIUM ION | non-polymer | 24.3 | 5 | Chemie (MG) | |||
| 7 | K (P) | PYROPHOSPHATE | non-polymer | 178.0 | 1 | Chemie (PPV) | |||
| 8 | L (D) | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
| 9 | M, N (A) | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 10 | O, P (A) | IMIDAZOLE | non-polymer | 69.1 | 2 | Chemie (IMD) | |||
| 11 | Q, R, S, T (T, P, D, A) | water | water | 18.0 | 221 | Chemie (HOH) |
Sequence modifications
A: 1 - 335 (UniProt: P06746)
| PDB | External Database | Details |
|---|---|---|
| His 336 | - | expression tag |
| His 337 | - | expression tag |
| His 338 | - | expression tag |
| His 339 | - | expression tag |
| His 340 | - | expression tag |
| His 341 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 48840.9 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 1013.7 | |
| All* | Total formula weight | 49854.7 |
