5VQP
Crystal structure of human pro-TGF-beta1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Transforming growth factor beta-1 | polymer | 363 | 41489.4 | 1 | UniProt (P01137) Pfam (PF00688) Pfam (PF00019) | Homo sapiens (Human) | TGF-beta-1 |
| 2 | B (B) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 1 | In PDB GlyTouCan (G15407YE) |
Sequence modifications
A: 1 - 361 (UniProt: P01137)
| PDB | External Database | Details |
|---|---|---|
| Gly -1 | - | expression tag |
| Pro 0 | - | expression tag |
| Ser 4 | Cys 33 | engineered mutation |
| Gln 107 | Asn 136 | engineered mutation |
| Gln 147 | Asn 176 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 41489.4 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 586.5 | |
| All* | Total formula weight | 42075.9 |
