5VNC

Glycogen synthase in complex with UDP and glucosamine

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Glycogen [starch] synthase isoform 2	polymer	720	81818.6	4	UniProt (P27472) Pfam (PF05693)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
2	E, G, J, L (A, B, C, D)	URIDINE-5'-DIPHOSPHATE	non-polymer		404.2	4	Chemie (UDP)
3	F, H, K, M (A, B, C, D)	6-O-phosphono-alpha-D-glucopyranose	non-polymer		260.1	4	Chemie (G6P)
4	I (C)	2-amino-2-deoxy-beta-D-glucopyranose	non-polymer		179.2	1	Chemie (GCS)
5	N (B)	water	water		18.0	1	Chemie (HOH)

Sequence modifications

A, B, C, D: 1 - 700 (UniProt: P27472)

PDB	External Database	Details
Met -19	-	initiating methionine
Gly -18	-	expression tag
Ser -17	-	expression tag
Ser -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
Ser -9	-	expression tag
Ser -8	-	expression tag
Gly -7	-	expression tag
Leu -6	-	expression tag
Val -5	-	expression tag
Pro -4	-	expression tag
Arg -3	-	expression tag
Gly -2	-	expression tag
Ser -1	-	expression tag
His 0	-	expression tag
Gln 169	Glu 169	engineered mutation
Ser 535	Ala 535	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	327274.5
Non-Polymers*	Number of molecules	9
	Total formula weight	2836.4
All*	Total formula weight	330110.8

*Water molecules are not included.