5VLA
Short PCSK9 delta-P' complex with Fusion2 peptide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Proprotein convertase subtilisin/kexin type 9 | polymer | 460 | 49784.1 | 1 | UniProt (Q8NBP7) Pfam (PF05922) Pfam (PF00082) | Homo sapiens (Human) | Neural apoptosis-regulated convertase 1,NARC-1,Proprotein convertase 9,PC9,Subtilisin/kexin-like protease PC9 |
| 2 | B (Z) | THR-VAL-PHE-THR-SER-TRP-GLU-GLU-TYR-LEU-ASP-TRP-VAL-MET-PRO-TRP-ASN-LEU-VAL-ARG-ILE-GLY-LEU-LEU | polymer | 30 | 3556.1 | 1 | synthetic construct | ||
| 3 | C, D (A) | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) | |||
| 4 | E, F (A, Z) | water | water | 18.0 | 127 | Chemie (HOH) |
Sequence modifications
A: 1 - 452 (UniProt: Q8NBP7)
| PDB | External Database | Details |
|---|---|---|
| Ser 167 | Arg 167 | engineered mutation |
| Asn 453 | - | expression tag |
| Ser 454 | - | expression tag |
| His 455 | - | expression tag |
| His 456 | - | expression tag |
| His 457 | - | expression tag |
| His 458 | - | expression tag |
| His 459 | - | expression tag |
| His 460 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 53340.2 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 80.2 | |
| All* | Total formula weight | 53420.3 |
