5VIG

Crystal structure of anti-Zika antibody Z006 bound to Zika virus envelope protein DIII

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, D (H, A)	Fab heavy chain	polymer	232	25110.2	2	UniProt (S6B291) Pfam (PF07686) Pfam (PF07654)	Homo sapiens (human)
2	B, E (L, B)	Fab light chain	polymer	213	23411.1	2	UniProt (P0DOX7) Pfam (PF07686) Pfam (PF07654)	Homo sapiens (human)	Immunoglobulin kappa light chain EU
3	C, F (Z, G)	Zika virus envelope protein DIII	polymer	110	11935.7	2	UniProt (A0A1I9ZK43) Pfam (PF02832) UniProt (by SIFTS) (A0A192GPS0)	Zika virus (ZIKV)
4	G (A)	CITRATE ANION	non-polymer		189.1	1	Chemie (FLC)

Sequence modifications

H, A: 1 - 105 (PDB: 5VIG)
H, A: 106 - 219 (UniProt: S6B291)

PDB	External Database	Details
His 220	-	expression tag
His 221	-	expression tag
His 222	-	expression tag
His 223	-	expression tag
His 224	-	expression tag
His 225	-	expression tag

L, B: 1 - 108 (PDB: 5VIG)
L, B: 109 - 214 (UniProt: P0DOX7)
Z, G: 299 - 407 (UniProt: A0A1I9ZK43)

PDB	External Database	Details
Met 298	-	initiating methionine

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	120914.0
Non-Polymers*	Number of molecules	1
	Total formula weight	189.1
All*	Total formula weight	121103.1

*Water molecules are not included.