5VH4

Crystal structure of Fab fragment of anti-TNFa antibody infliximab in an I-centered orthorhombic crystal form

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C (H, A)	Infliximab Fab Heavy Chain	polymer	226	24356.2	2		Mus musculus Homo sapiens
2	B, D (L, B)	Infliximab Fab Light Chain	polymer	214	23460.9	2		Mus musculus Homo sapiens
3	E, I (H, A)	NICOTINAMIDE-ADENINE-DINUCLEOTIDE	non-polymer		663.4	2	Chemie (NAD)
4	F, G, H, J, K (H, L, A, B)	1,2-ETHANEDIOL	non-polymer		62.1	5	Chemie (EDO)
5	L, M, N, O (H, L, A, B)	water	water		18.0	854	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	95634.1
Non-Polymers*	Number of molecules	7
	Total formula weight	1637.2
All*	Total formula weight	97271.3

*Water molecules are not included.