5VEC

Crystal Structure of the R515L missense variant of human PGM1

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Phosphoglucomutase-1	polymer	585	64147.7	2	UniProt (P36871) Pfam (PF02878) Pfam (PF02879) Pfam (PF02880) In PDB	Homo sapiens (Human)	PGM 1,Glucose phosphomutase 1
2	A, B	SULFATE ION	non-polymer		96.1	6	Chemie (SO4)
3	A, B	MAGNESIUM ION	non-polymer		24.3	2	Chemie (MG)
4	A, B	GLYCEROL	non-polymer		92.1	6	Chemie (GOL)
5		water	water		18.0	635	Chemie (HOH)

Sequence modifications

A, B: 1 - 562 (UniProt: P36871)

PDB	External Database	Details
Met -22	-	expression tag
His -21	-	expression tag
His -20	-	expression tag
His -19	-	expression tag
His -18	-	expression tag
His -17	-	expression tag
His -16	-	expression tag
Ser -15	-	expression tag
Ser -14	-	expression tag
Gly -13	-	expression tag
Val -12	-	expression tag
Asp -11	-	expression tag
Leu -10	-	expression tag
Gly -9	-	expression tag
Thr -8	-	expression tag
Glu -7	-	expression tag
Asn -6	-	expression tag
Leu -5	-	expression tag
Tyr -4	-	expression tag
Phe -3	-	expression tag
Gln -2	-	expression tag
Ser -1	-	expression tag
Asn 0	-	expression tag
Leu 515	Arg 515	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	128295.4
Non-Polymers*	Number of molecules	14
	Total formula weight	1177.6
All*	Total formula weight	129472.9

*Water molecules are not included.