5VEA
HIV Protease (PR) with TL-3 in active site and 4-methylbenzene-1,2-diamine in exosite
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | HIV-1 protease | polymer | 99 | 10831.8 | 1 | UniProt (Q72863) Pfam (PF00077) UniProt (by SIFTS) (P12497) In PDB | Human immunodeficiency virus 1 | |
| 2 | A | benzyl [(1S,4S,7S,8R,9R,10S,13S,16S)-7,10-dibenzyl-8,9-dihydroxy-1,16-dimethyl-4,13-bis(1-methylethyl)-2,5,12,15,18-pentaoxo-20-phenyl-19-oxa-3,6,11,14,17-pentaazaicos-1-yl]carbamate | non-polymer | 909.1 | 1 | BIRD (PRD_000434) Chemie (3TL) | |||
| 3 | A | 4-methylbenzene-1,2-diamine | non-polymer | 122.2 | 1 | Chemie (9AY) | |||
| 4 | A | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 3 | Chemie (DMS) | |||
| 5 | water | water | 18.0 | 47 | Chemie (HOH) |
Sequence modifications
A: 1 - 99 (UniProt: Q72863)
| PDB | External Database | Details |
|---|---|---|
| Lys 7 | Gln 15 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 10831.8 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 1265.6 | |
| All* | Total formula weight | 12097.5 |
