5VDP
Human cyclic GMP-AMP synthase (cGAS) in complex with 2',3'-cGAMP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Cyclic GMP-AMP synthase | polymer | 363 | 42536.1 | 2 | UniProt (Q8N884) Pfam (PF03281) Pfam (PF20266) In PDB | Homo sapiens (Human) | h-cGAS,2'3'-cGAMP synthase,Mab-21 domain-containing protein 1 |
| 2 | A, B | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 3 | A, B | SULFATE ION | non-polymer | 96.1 | 5 | Chemie (SO4) | |||
| 4 | A, B | cGAMP | non-polymer | 674.4 | 2 | Chemie (1SY) | |||
| 5 | water | water | 18.0 | 129 | Chemie (HOH) |
Sequence modifications
A, B: 161 - 522 (UniProt: Q8N884)
| PDB | External Database | Details |
|---|---|---|
| Met 160 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 85072.2 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 1960.0 | |
| All* | Total formula weight | 87032.2 |
